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15 Natural Treatments for Pyroluria

This type of disorder is considered as a familial disorder. It is a condition which is characterized by an above – average amount of kryptopyrroles in the body. These substances are innately harmless but the high levels of this element systemically bind with the zinc and Vitamin B6 which is preventing the body and brain from using these important nutrients. The most common symptoms of pyroluria are schizophrenia; noise and other tactile sensitivities; depression; mood swings; poor tolerance of physical and emotional stress.

Those people who have psychiatric disorders, such as schizophrenia have high levels of pyroles. Also those children who are emotionally disturbed and alcoholics have abnormally high pyrole content. It is very important to be discovered if someone has zinc or Vitamin B6 deficiency because these are critical elements for our bodies and also they can help in a better treatment of pyroluria. Many people have noticed improvements in their condition when their doctors have given them the right treatment.

In many cases the symptoms of pyroluria are mistaken with other diseases so it is very important to get the proper diagnosis and treatment. You need to talk with your doctor if you suffer from pyroluria before you start using some of the below mentioned home remedies for this condition. Here are some home remedies for pyroluria:

Vitamin C help in pyroluria

This is a powerful antioxidant which can aid in the chelation of pyrroles and copper in the body. When you are taking this natural cure on daily basis, then it can help to eliminate free radicals and other toxins in the body. Also this vitamin can support the function of your immune system and it will boost it.

pyroluria foods to avoid

Vitamin B6

This vitamin is involved in over 100 enzyme reactions and also it is involved in the general metabolism. Also this nutrient is depleted by the pyroluria so it is very important to get it. If you are taking Vitamin B6 supplements, then you need to talk with your doctor about the recommended dosage for you. Also it is known that this vitamin can support the immune function. Also you can consume foods rich in this vitamin such as hazelnuts; molasses and sorghum syrup; pork tenderloin; sunflower and sesame seeds; yellow – fin tuna, salmon and cod; liver; garlic, especially the raw garlic; pistachios; chili powder, paprika, garlic and other herbs/spices; rice bran and brown rice. [1,2]

Zinc help in pyroluria

This is a trace element which is involved in the immune support and in the fight against infection. We know that the pyroluria depletes zinc levels so it is very important to supplement the zinc. This is a trace mineral which means that it should be monitored closely and to avoid overdose of it. Also you can consume foods which are rich in zinc, such as white mushrooms; mung beans (also you can consume chickpeas, kidney beans and baked beans); pork and chicken; cocoa and chocolate; cashews (also hazelnuts; peanuts; walnuts; almonds; pecans and pine nuts); pumpkin and squash seeds (also flax and sunflower chia); spinach; wheat germ; beef and lamb; seafood, such as lobster, crab and oysters. [1,2]

Prevent infections in your body

It is known fact that when the immune system is working overtime to fight against infections, then it is throwing off a lot of oxidation and this is a reason why you feel fatigued when you get sick. You should talk with your doctor about a good strategy to avoid cold and infections because it also can help you in the treatment of pyroluria.

Cut the caffeine and other stimulants

You should avoid coffee and other stimulants because this will help you to get in the adrenal repair mode. You should start slowly not to force your body because if you try to quit from everything that you have used, then it may have some adverse effects. Coffee has caffeine but also there are other products which have this component so you should avoid all products that have coffee in it. [3]

Vitamin B3

This vitamin is also known as niacinamide. It is necessary vitamin for the production of tryptophan which is needed for the production of serotonin [4]. You should take this vitamin because it can help you to speed the recovery process of pyroluria.

Get enough sleep

It is very important to get enough sleep and to have good sleeping routines because they can help you in the treatment of pyroluria. You should not sleep too much or too little so you should aim to sleep eight to nine hours per night. Many people who have pyroluria suffer from insomnia too so you should talk with your doctor if this is your case to learn how to manage your sleeping and improve it.

Pantothenic acid

This acid is needed to rebuild the adrenal glands which have been exhausted from the coping with the ongoing tension that is caused by the pyroluria. You should add it in a supplement form because it can help you to overcome the fatigue and weakness which you feel.

Regular exercise

It is recommended doing regular but gentle exercise. When you suffer from pyroluria, then it does not mean that you should rest all the time. You should still be active. If you are lying on the couch or you are sitting in your comfortable chair, then it can be counter-productive for your health. We know that our bodies are designed to move and not to lay on couch all the time.

This is a reason why you should aim to do gentle movements, such as easy and non – strenuous yoga movements, Tai Chi or Qi Gong, rowing or exercise machines, riding bike and walking in nature. When you are doing these exercises, then this can help you to rid of the stress. They will give your body a chance to repair and recover.

Minimize external conflict

You should stop arguing with people and you should walk away if some person wants to have a verbal fight first. You should get away from consistently stressful relationships.

Lifestyle changes

You need to do things in which you enjoy, such as reading, taking time to relax, listening to music and change in occupation if it is not making you happy. If you cannot change your job, then you should find some hobbies to do in your free time which will give you extra energy and motivation.

Avoid toxins

You should choose organic foods whenever is possible. You should quit smoking if you are doing it. Also you should avoid off – gassing from furniture and carpets, plastics, exhaust fumes and artificially scented products (like fabric softeners, laundry dryer sheets, room fresheners, etc.). You should check your cleaning products and personal care products and you should switch to more natural or homemade alternatives. [5]


When you are taking Vitamin B6 in large amounts, then it can deplete the magnesium levels. When you are adding magnesium in your diet, then it can reduce the hypersensitivity and irritability to light and sound.

Avoid alcohol

It is known that the alcohol can make people to feel anxious, stress and they have low self esteem. Also this product is making hormonal imbalance in your body. You need to stop drinking alcohol and if you cannot do it by yourself, then you need to talk with your doctor as soon as possible. [6]

Clean diet

It is very important for your diet to be effective. This means that you should eat a clean and whole food diet. You should avoid chemicals. Before you buy some food, you need to read ingredient labels. Also you should not eat junk food if you suffer from pyroluria. You need to eat home cooked food as much as possible. Also you need to avoid gluten. One of the best choices for people who suffer from pyroluria is to eat grain free diet. Also you should eat foods that are rich in zinc, Vitamin B6 and GLA.

You need to reduce the processed foods and sugars in your diet. We know that processing sugar in the body can cause high amounts of oxidation. Also the processed food can have high levels of sugar and chemicals which are creating oxidation. It is known that when you are eating large and infrequent meals, this can worsen the oxidation so this is a reason why you should eat smaller meals throughout your day. Also you should eat good quality dairy products, eggs, seeds, nuts, fruits, chicken, fish, meat and green leafy vegetables. You should avoid meat and meat products.


It is known that this nutrient is depleted with zinc so it has to be taken in high doses as a natural treatment for pyroluria. This mineral is necessary for the metabolism of certain proteins. Also this mineral is important for the joint development and neurotransmitter production.  [7]


[1] McGinnis WR, Audhya T, Walsh WJ, et al. Discerning the mauve factor, Part 1. Alternative Therapies in Health and Medicine. 2008;14(2):40-50.

[2] Scott T. How zinc and Vitamin B6 prevent pyroluria and social anxiety. The Anxiety Summit. 2014.

[3] Ryu KY, Roh J. The effects of high peripubertal caffeine exposure on the adrenal gland in immature male and female rats. Nutrients. 2019;11:951.

[4] Fukuwatari T, Shibata K. Nutritional aspect of tryptophan metabolism. International Journal of Tryptophan Research. 2013;6(Suppl1):3–8.

[5] Mie A, Andersen HR, Gunnarsson S, et al. Human health implications of organic food and organic agriculture: a comprehensive review. Environmental Health. 2017;16:111.

[6] Keyes KM, Hatzenbuehler ML, Grant BF, Hasin DS. Stress and alcohol: Epidemiologic evidence. Alcohol Research. 2012;34(4):391–400.

[7] Nakamura M, Miura A, Nagahata T, et al. Low zinc, copper, and manganese intake is associated with depression and anxiety symptoms in the Japanese working population: Findings from the eating habit and well-being study. Nutrients. 2019;11(4):847.

Neem Mayur
Neem Mayur
Mayur Neem, a certified dietician having more than 5 years of experience in the field of diet practice. He is working as a diet expert and offering services to body builders, sports persons, celebrities, etc. He is lover of natural remedies and loves to spend most of his free time in his organic farm and offers expert advice on organic farming to local farmers. He is available through [email protected]


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